From the Laurelton murders in 1985 to Cyrus Renault in 2025, Pier 54 goes through every serial killer in General Hospital history: Ryan Chamberlain, Franco Baldwin, the Text Message Killer, the Angel of Mercy, the Hook, the masked killer at the Quartermaine mansion, the General Homicide killer from Port Charles, and vampires Caleb Morley and Joshua Temple. Plus why Cesar Faison did not make the list.